Table 2. Spearman correlation coefficients between sense and antisense transcript levels.
Q1-4 indicates quartiles, with Q1 indicating the genes with highest sense expression values. For the human liver sample, we performed the analysis only for the top three quartiles since genes with zero expression level dominated the fourth quartile. The minimum and maximum correlation coefficients obtained after 1000 permutations were reported (thus p<0.001). Similar trends were observed for yeast after the removal of potentially overlapping transcripts (see also Table S4).
Yeast | ||||
---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | |
Actual Correlation | −0.11 | 0 | −0.01 | 0.36 |
1000 Permutations, minimum | −2.39E-05 | −5.55E-05 | −3.79E-05 | −6.78E-05 |
1000 Permutations, maximum | 9.05E-05 | 7.01E-05 | 8.47E-05 | 7.84E-05 |
Human Liver | |||
---|---|---|---|
Q1 | Q2 | Q3 | |
Actual Correlation | −0.11 | 0.02 | 0.12 |
1000 Permutations, minimum | −9.59E-05 | −3.40E-05 | −9.00E-05 |
1000 Permutations, maximum | 9.25E-05 | 9.80E-06 | 5.69E-07 |