Table 8. Evidence of benefits associated with ePrescribing.

Benefits
Reference ID	Surrogate Outcomes	Guideline Adherence	Safer Prescribing	Communication	Patient Outcomes	Resource/Cost Savings	Time Savings
Ammenwerth 2008	Pot. ADEs +/+ +	N/A	MEs ++	N/A	ADEs +	N/A	N/A
Bryan 2008	+	+	N/A	N/A	+/-	+	N/A
Chatellier 1998	+/++	N/A	++/+	N/A	Death +/-Haemorrhage +/-Thromboembolic events +/-	N/A	N/A
Clamp 2005	++	+	MEs ++	+	ADEs +	+	+
Delpierre 2004	+/-	+	MEs+	N/A	+/-	N/A	N/A
Duriex 2008	+/++	+	+/++	N/A	Death +/-	+/++	N/A
Eslami 2007	+	+/+ +	+/-	N/A	+/-	+	+
Eslami 2008	+	+/+ +	+	+	+/-	+	+
Eslami 2009	+	+	N/A	N/A	+/-	N/A	N/A
Fitzmaurice 1998	+	N/A	+	N/A	+	N/A	N/A
Garg 2005	+/++	+	+/-	N/A	+/-	+/-	N/A
Hider 2002	+/++	+/+ +	+	+/+ +	+	+	N/A
Jamal 2009	+	+/++	+	N/A	+/-	+	N/A
Mitchell 2001	+	N/A	N/A	N/A	+/-	+	+
Mollon 2009	+/++	N/A	N/A	N/A	+/-	+/-	N/A
Niyazkhani 2009	+	N/A	N/A	+/++	N/A	N/A	+/++
Poissant 2005	N/A	N/A	N/A	N/A	N/A	N/A	+/-
Rothschild 2004	+/++	+	MEs ++	N/A	ADEs +	+	+
Schedlbauer 2009	+/++	+	MEs ++	N/A	Renal ADEs+Falls+	+	N/A
Shamliyan 2008	+	N/A	MEs ++	N/A	ADEs +	N/A	N/A
Shekelle 2006	+/+ +	N/A	MEs +	N/A	ADEs +	+/-	N/A
Shiffman 1999	N/A	+/+ +	N/A	N/A	+/-	N/A	N/A
Shojania 2009	+	+	N/A	N/A	+	N/A	N/A
Sintchenko 2007	++	+	N/A	N/A	Death +/-ADEs +	N/A	N/A
Tan 2005	+	N/A	MEs +	N/A	+/-	+/-	+
Van Rosse 2009	+/+ +	N/A	++	+	Death +/-ADEs +/-	N/A	+
Wolfstadt 2008	N/A	N/A	N/A	N/A	ADEs +/-	N/A	N/A
Yourman 2008	+	+	N/A	N/A	+/-	+/-	N/A

Evidence of benefits: N/A, not assessed; +/-, none; +, weak; +/++, weak to moderate; ++, moderate.