Table 2.

Analysis of covariance of PGC1α rs7665116 in Italian HD patients

Model	R2	ΔR2	P value
HD CAG	0.4444		< 0.0001*
HD CAG + PGC1α rs7665116
1-1 vs 1-2 vs 2-2	0.4682	0.0238	0.0172*
1-1 vs 1-2 + 2-2	0.4681	0.0237	0.0045*

The level of significance was set to P = 0.05; n = 312

HD CAG expanded CAG allele in huntingtin