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Mean ages-at-onset of the different rs2970870 genotypes in HD patients with ≤ 55 CAGs
| Genotype | Number of patientsa | Mean CAGexp (SE) | Mean AAOb (SE) |
|---|---|---|---|
| T/T | 262 | 44.9 (0.21) | 46.37 (0.77) |
| T/C | 404 | 44.5 (0.15) | 48.19 (0.62) |
| C/C | 118 | 45.4 (0.33) | 43.67 (1.15) |
CAGexp, expanded CAG repeat number; SE, standard error; T, major allele g.-1437T; C, minor allele g.-1437C.
an = 784.
bt-test: Patients ≤ 60 CAG repeats and genotype C/C differ significantly from patients with T/T and T/C genotype (p = 0.0039).
