Table 1.
Striatal monoamine levels (ng/mg tissue)
| Mice | Dopamine | DOPAC | HVA |
|---|---|---|---|
| Saline | |||
| Wild type | 12.2 ± 0.2 | 2.1 ± 0.2 | 1.8 ± 0.1 |
| Bax+/− | 13.3 ± 0.3 | 2.0 ± 0.1 | 1.7 ± 0.1 |
| Bax−/− | 13.4 ± 0.4 | 2.4 ± 0.1 | 1.6 ± 0.2 |
| MPTP | |||
| Wild type | 0.5 ± 0.1 | 0.3 ± 0.05 | 0.2 ± 0.01 |
| Bax+/− | 3.1 ± 0.3* | 0.6 ± 0.06 | 0.6 ± 0.04* |
| Bax−/− | 4.1 ± 0.2** | 1.3 ± 0.2** | 1.0 ± 0.1** |
DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid. *, P < 0.05, compared to MPTP-injected wild-type mice; **, P < 0.05, compared to MPTP-injected wild-type and MPTP-injected Bax+/− mice; Newman-Keuls post hoc test. Data represent means ± SEM for 4–6 mice per group.