Table 1.
Characteristic | Nontumor brain tissue (n = 7) | Tumor histology and grade of glioma tissues (n = 131) |
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Primary glioblastoma (n = 20) | Secondary glioblastoma (n = 12) | Grade 3 astrocytoma (n = 9) | Grade 2 astrocytoma (n = 20) | Grade 3 oligoastrocytoma (n = 9) | Grade 2 oligoastrocytoma (n = 22) | Grade 2 oligodendroglioma (n = 20) | Ependymoma (n = 15) | Pilocytic astrocytoma (n = 4) | ||
Age at diagnosis, y | ||||||||||
Median | 33 | 55 | 34.5 | 40 | 40 | 40 | 33 | 35.5 | 41 | 28.5 |
Range | 23–42 | 21–78 | 18–49 | 23–57 | 21–64 | 26–52 | 19–48 | 20–59 | 19–70 | 22–39 |
Sex, No. (%) | ||||||||||
Female | 3 (43) | 7 (35) | 4 (33) | 6 (67) | 10 (50) | 4 (44) | 9 (41) | 10 (50) | 4 (27) | 2 (50) |
Male | 4 (57) | 13 (65) | 8 (67) | 3 (33) | 10 (50) | 5 (56) | 13 (59) | 10 (50) | 11 (73) | 2 (50) |
Race, No. (%) | ||||||||||
White | — | 18 (90) | 11 (92) | 5 (56) | 17 (85) | 7 (78) | 16 (73) | 18 (90) | 12 (80) | 4 (100) |
Hispanic | — | 1 (5) | 1 (8) | 2 (22) | 1 (5) | 0 | 1 (4) | 1 (5) | 2 (13) | 0 |
American Indian | — | 0 | 0 | 0 | 1 (5) | 0 | 0 | 0 | 0 | 0 |
Asian | — | 0 | 0 | 1 (11) | 1 (5) | 0 | 2 (9) | 1 (5) | 0 | 0 |
Unknown | 7 (100) | 1 (5) | 0 | 1 (11) | 0 | 2 (22) | 3 (14) | 0 | 1 (7) | 0 |
Survival, d | ||||||||||
Median | NA | 759 | 1244 | 1933 | 1584 | 3007 | 2937 | 2532 | 2498 | 2789 |
Range | NA | 108–2477 | 466–4973 | 516–4494 | 305–4043 | 603–6459 | 612–5843 | 4–5988 | 478–5983 | 948–3279 |
Nontumor brain tissues (n = 7) were obtained from cancer-free patients who underwent temporal lobe resection for treatment of epilepsy at the University of California San Francisco Medical Center. Glioma tissues (n = 131) were obtained between 1990 and 2003 from the University of California San Francisco Brain Tumor Research Center Tissue Bank.