Table 1.
Patient, treatment, and disease characteristics*
| No. (%) | ||
| Socioeconomic and demographic characteristics | ||
| Age group, y | ||
| <40 | 53 (5.3) | |
| 40–49 | 230 (23.1) | |
| 50–64 | 350 (35.2) | |
| ≥65 | 361 (36.3) | |
| Insurance | ||
| Private | 395 (39.7) | |
| Medicare and private | 73 (7.3) | |
| Medicare | 328 (33.0) | |
| Medicaid/other/unknown | 198 (19.9) | |
| Race | ||
| White | 789 (79.4) | |
| Black | 152 (15.3) | |
| Asian | 10 (1.0) | |
| Other | 43 (4.3) | |
| Clinical characteristic | No. (%) | |
| No. of comorbid conditions | ||
| 0 | 339 (34.1) | |
| 1 | 330 (33.2) | |
| ≥2 | 325 (32.7) | |
| Family history of breast cancer | ||
| Yes | 201(20.2) | |
| No | 672 (67.6) | |
| Unknown | 121 (12.2) | |
| Menopausal status | ||
| Premenopausal | 241 (24.2) | |
| Perimenopausal | 38 (3.8) | |
| Postmenopausal | 637 (64.1) | |
| Unknown | 78 (7.8) | |
| Detected with mammogram | 853 (85.8) | |
| Mammographic tumor size unknown† | 785 (79.0) | |
| Calcifications | ||
| Yes | 807 (81.2) | |
| No | 142 (14.3) | |
| Unknown | 45 (4.5) | |
| Continuous variables | Mean (SD) | |
| Census block group variables (N = 994) | ||
| Percent living below poverty | 9.7 (11.2) | |
| Percent black | 17.53 (1.1) | |
| Mammographic tumor size (cm) | ||
| If known (N = 199)† | 1.8 (1.4) | |
| Pathology characteristic | Treatment pathology,‡ No. (%) | Outcome pathology,§ No. (%) |
| Histology║ | ||
| Comedo | 318 (32.0) | 335 (33.7) |
| Cribriform | 371 (37.3) | 388 (39.0) |
| Apocrine | 12 (1.2) | 12 (1.2) |
| Solid | 217 (20.8) | 217 (21.8) |
| Papillary | 80 (7.5) | 80 (8.0) |
| Micropapillary | 129 (12.8) | 129 (13.0) |
| Other | 24 (2.4) | 27 (2.7) |
| Unknown | 48 (4.8) | 55 (5.5) |
| Multifocal disease | ||
| No | 146 (14.7) | 140 (14.1) |
| Yes | 345 (34.7) | 391 (39.3) |
| Unknown | 503 (50.6) | 463 (46.6) |
| Extensive DCIS | 99 (10.0) | 59 (5.9) |
| Margin status | ||
| Negative (≥2 mm) | 550 (55.3) | 749 (75.4) |
| Close (<2 mm) | 250 (25.2) | 199 (20.0) |
| Positive | 194 (19.5) | 46 (4.6) |
| Nuclear grade | ||
| High | 133 (13.4) | 134 (13.5) |
| Medium | 193 (19.4) | 193 (19.4) |
| Low | 425 (42.8) | 437 (44.0) |
| Unknown | 243 (24.4) | 230 (23.1) |
| Necrosis | ||
| Present | 553 (55.6) | 565 (56.8) |
| Absent | 386 (38.8) | 320 (32.2) |
| Punctate | 55 (5.5) | 57 (5.7) |
| Central | 449 (45.2) | 463 (46.6) |
| Treatments, margins, and ipsilateral breast tumor recurrences | ||
| Treatments and margins, No. (% of total)* | Recurrences, No. (% of women with specified treatment)* | |
| Mastectomy | 383 (38.5) | 7 (1.8) |
| With RT¶ | 9 (0.9) | 2 (22.2) |
| Without RT | 374 (97.6) | 5 (1.4) |
| BCS | 611 (61.5) | 52 (8.5) |
| With RT# | 357 (36.8) | 19 (5.3) |
| Without RT | 254 (25.5) | 33 (13.0) |
| Negative margins | 749 (75.3) | 31 (4.1) |
| Close margins | 199 (20.0) | 19 (9.5) |
| Positive margins | 46 (4.6) | 9 (19.6) |
*
Total N = 994; number of women with recurrences = 59; BCS = breast-conserving surgery; NA = not applicable; RT = radiation therapy.
†
Mammographic tumor size was often not applicable and therefore not recorded (unknown).
‡
Refers to pathology information through the point at which the final surgical decision was made.
§
Refers to the final pathology information accumulated through the final surgical procedure.
║
Histology categories are not mutually exclusive and therefore percents sum to more than 100%.
¶
2.3% of those having mastectomy.
#
59.9% of those having BCS.