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. 2011 Jan 18;6(1):e14545. doi: 10.1371/journal.pone.0014545

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Pitter et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Four-to-six week old nestin-tv-a/ink4a-arf-/-/pten^fl/fl mice are stereotactically injected with DF-1 cells expressing the RCAS-PDGF-B virus and from high-grade gliomas with PTEN intact. (B) Four-to-six week old nestin-tv-a/ink4a-arf-/-/pten^fl/fl mice are stereotactically injected with DF-1 cells expressing the RCAS-PDGF-B virus and DF-1 cells expressing RCAS-Cre virus and from high-grade tumors with PTEN deleted.