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. 2010 Dec 15;7:45. doi: 10.1186/1742-6405-7-45

Table 1.

Characteristics of N = 44,491 participating patients, by year at first presentation

Total 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 p-value
N = 44,491 N = 4,479 N = 4,412 N = 4,857 N = 5,262 N = 4,258 N = 4,063 N = 3,688 N = 3,773 N = 3,486 N = 3,354 N = 2,859
Age (years)
18-< 50 35,093 79% 3,698 83% 3,624 82% 3,953 81% 4,244 81% 3,344 79% 3,158 78% 2,855 77% 2,912 77% 2,709 78% 2,516 75% 2,080 73% < 0.01
≥50 9,398 21% 781 17% 788 18% 904 19% 1,018 19% 914 21% 905 22% 833 23% 861 23% 777 22% 838 25% 779 27% < 0.01
AIDS-defining illness
18-< 50 3,390 10% 417 11% 385 11% 362 9% 370 9% 344 10% 331 10% 277 10% 270 9% 251 9% 208 8% 175 8% < 0.01
≥50 1,242 13% 142 18% 127 16% 119 13% 121 12% 133 15% 119 13% 105 13% 105 12% 102 13% 95 11% 74 9% < 0.01
CD4+ T-cell Count (cells/mm3)
18-< 50
Median 298 269 277 275 284 293 313 296 312 323 333 336 < 0.01
IQR 112-493 100-467 96-481 99-464 104-494 100-494 124-501 114-504 127-499 134-500 141-512 152-522
≥50
Median 251 203 211 246 261 234 272 274 261 272 273 266 < 0.01
IQR 90-457 80-390 65-403 88-440 102-464 88-443 111-457 92-475 83-487 81-511 107-491 111-494

P-values calculated using Cochran-Armitage test for categorical variables or Cuzick's test for continuous variables.