Table 3.
Laboratory values of patients with and without immune restoration disease before and after HAART commencement, at Zewditu Memorial Hospital, Addis Ababa, Ethiopia
| Variables | Patients with IRD (n = 170) | Patients without IRD (n = 996) | ||||
|---|---|---|---|---|---|---|
| Mean (SD) values at baseline | Mean (SD) values after 6 months | P-value | Mean (SD) values at baseline | Mean (SD) values after 6 months | P-value | |
| CD4+ (cells/μl) | 84 (57.8)* | 185(94.8) | 0.001 | 116 (69.4) | 236(120) | 0.001 |
| WBC (cells/μl) | 4246(1948) | 5725 (3124) | 0.001 | 4814 (1729) | 6516(2072) | 0.001 |
| Hgb (gm/dl) | 11.5(2.9) | 12.1 (4.7) | 0.400 | 12.2 (2.7) | 13.9 (3.8) | 0.001 |
| AST (IU/L) | 30.7(23.2) | 37.8(28.8) | 0.020 | 30(25.7) | 43 (34.2) | 0.001 |
| ALT (IU/L) | 25.3(20.2) | 33.4(28.9) | 0.003 | 25.1(23) | 39 .2(34) | 0.001 |
| ALP (IU/L) | 208(160) | 213(167) | 0.770 | 190 (149.9) | 251 (212) | 0.001 |
* Mean (SD); IRD, immune restoration disease; WBC, white blood cell; Hgb, hemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase.