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. 2001 Feb 27;98(5):2843–2848. doi: 10.1073/pnas.051626398

Figure 4.

Figure 4

Effects of central Ucn II on food intake and gross motor activity. (A) Mean (± SEM; n = 3–6 per group) cumulative nighttime food intake (g) following i.c.v. administration of 1 μg of CRF, Ucn, or Ucn II. Both CRF and Ucn significantly reduced food intake compared with saline-injected controls, beginning at 4 h postinjection, whereas the effect of Ucn II was not manifest until 6 h after treatment. *, P < 0.002 (CRF and Ucn vs. saline); **, P < 0.002 (CRF, Ucn, and Ucn II vs. saline). (B) Telemetric measures of gross motor activity were significantly elevated in animals that received i.c.v. injections of CRF; neither Ucn nor Ucn II significantly affected motor activity. *, P < 0.001 (CRF vs. saline).

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