Table 2.
Pulmonary function tests of patients with severe asthma
| Characteristics | FAO (n = 119) | RAO (n = 116) | P-value |
|---|---|---|---|
| FEV1, initial, predicted % | 54.8 ± 19.9 | 74.3 ± 22.5 | <0.001 |
| FEV1/FVC, initial, predicted % | 56.3 ± 11.1 | 77.6 ± 10.6 | <0.001 |
| FEV1/FVC, 3 months after enrollment, predicted % | 57.2 ± 10.6 | 80.0 ± 6.7 | <0.001 |
| FEV1/FVC, 12 months after enrollment, predicted % | 58.9 ± 9.6 | 80.9 ± 7.1 | <0.001 |
| Baseline PC20, mg/dL* | 2.7 ± 4.1 | 5.6 ± 6.4 | 0.036 |
*Baseline methacholine bronchial provocation tests were done in 65 subjects:
33 patients with FAO (n = 119), 32 patients with RAO (n = 116)
Abbreviations:
FAO, fixed airway obstruction; RAO, reversible airway obstruction; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; PC20, provocation concentration that caused a 20% decrease in FEV1
Data are presented as mean ± SD.