Table 3.
Association between SNPs from DUSP12-ATF6 and clinical features related to glucose metabolism in the normal glucose regulation subjects
| SNP | Fasting glucose | 2 h glucose | Fasting insulin | HOMA-IR | HOMA-B | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Beta | SE | P | Beta | SE | P | Beta | SE | P | Beta | SE | P | Beta | SE | P | |
| rs10799941 | 0.0065 | 0.0164 | 0.6933 | 0.0325 | 0.0387 | 0.4024 | -0.0087 | 0.0226 | 0.7019 | -0.0076 | 0.0237 | 0.7492 | -0.0164 | 0.0249 | 0.5116 |
| rs1503814 | 0.0098 | 0.0179 | 0.5833 | 0.0247 | 0.0425 | 0.5613 | 0.0023 | 0.0251 | 0.9273 | 0.0065 | 0.0262 | 0.8036 | -0.0135 | 0.0277 | 0.6264 |
| rs12021510 | 0.0073 | 0.0322 | 0.8203 | -0.0795 | 0.0760 | 0.2953 | 0.0039 | 0.0452 | 0.9319 | 0.0054 | 0.0473 | 0.9086 | -0.0021 | 0.0499 | 0.9670 |
| rs12121310 | 0.0288 | 0.0173 | 0.0963 | 0.0740 | 0.0411 | 0.0719 | -0.0066 | 0.0241 | 0.7858 | 0.0010 | 0.0253 | 0.9678 | -0.0400 | 0.0267 | 0.1346 |
| rs1063178 | 0.0298 | 0.0165 | 0.0722 | 0.0356 | 0.0392 | 0.3639 | 0.0083 | 0.0230 | 0.7192 | 0.0162 | 0.0240 | 0.5008 | -0.0259 | 0.0254 | 0.3068 |
| rs1063179 | -0.0178 | 0.0192 | 0.3541 | 0.0082 | 0.0454 | 0.8561 | -0.0241 | 0.0262 | 0.3590 | -0.0258 | 0.0274 | 0.3483 | -0.0090 | 0.0288 | 0.7552 |
| rs3820449 | 0.0216 | 0.0178 | 0.2256 | 0.0739 | 0.0421 | 0.0791 | -0.0179 | 0.0247 | 0.4687 | -0.0113 | 0.0259 | 0.6627 | -0.0489 | 0.0273 | 0.0737 |
| rs2070151 | -0.0187 | 0.0184 | 0.3094 | -0.0112 | 0.0435 | 0.7970 | 0.0023 | 0.0254 | 0.9295 | -0.0061 | 0.0266 | 0.8182 | 0.0328 | 0.0280 | 0.2426 |
| rs2271013 | -0.0203 | 0.0184 | 0.2704 | -0.0126 | 0.0435 | 0.7728 | 0.0014 | 0.0252 | 0.9559 | -0.0073 | 0.0264 | 0.7822 | 0.0330 | 0.0278 | 0.2367 |
| rs2271012 | -0.0196 | 0.0186 | 0.2934 | -0.0193 | 0.0440 | 0.6615 | 0.0086 | 0.0257 | 0.7376 | 0.0004 | 0.0269 | 0.9883 | 0.0376 | 0.0285 | 0.1866 |
| rs2070150 | -0.0177 | 0.0185 | 0.3397 | -0.0154 | 0.0438 | 0.7249 | 0.0062 | 0.0257 | 0.8106 | -0.0020 | 0.0269 | 0.9405 | 0.0349 | 0.0283 | 0.2178 |
| rs1135983 | -0.0168 | 0.0185 | 0.3633 | -0.0192 | 0.0438 | 0.6609 | 0.0128 | 0.0256 | 0.6180 | 0.0046 | 0.0268 | 0.8642 | 0.0427 | 0.0283 | 0.1314 |
| rs10918029 | 0.0075 | 0.0197 | 0.7027 | 0.0282 | 0.0467 | 0.5451 | -0.0102 | 0.0271 | 0.7066 | -0.0071 | 0.0284 | 0.8029 | -0.0177 | 0.0300 | 0.5561 |
| rs2340721 | -0.0023 | 0.0174 | 0.8958 | 0.0488 | 0.0410 | 0.2342 | -0.0074 | 0.0239 | 0.7581 | -0.0064 | 0.0250 | 0.7988 | -0.0125 | 0.0264 | 0.6346 |
| rs2341475 | 0.0202 | 0.0187 | 0.2810 | -0.0207 | 0.0445 | 0.6419 | 0.0021 | 0.0257 | 0.9350 | 0.0093 | 0.0269 | 0.7299 | -0.0226 | 0.0289 | 0.4332 |
| rs10918215 | 0.0022 | 0.0167 | 0.8941 | -0.0441 | 0.0396 | 0.2647 | 0.0120 | 0.0232 | 0.6054 | 0.0093 | 0.0243 | 0.7006 | 0.0193 | 0.0256 | 0.4501 |
| rs7522210 | 0.0001 | 0.0166 | 0.9945 | -0.0425 | 0.0394 | 0.2809 | 0.0095 | 0.0230 | 0.6810 | 0.0061 | 0.0241 | 0.8001 | 0.0213 | 0.0253 | 0.3991 |
| rs2499855 | 0.0153 | 0.0266 | 0.5654 | -0.0842 | 0.0630 | 0.1814 | 0.0172 | 0.0367 | 0.6391 | 0.0199 | 0.0384 | 0.6045 | 0.0023 | 0.0407 | 0.9546 |