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Mean whole brain uptake of (R)-[11C]verapamil, expressed as SUV (radioactivity normalized to injected dose and rat weight), as function of time in the four rat groups. Vertical bars represent standard deviation. No difference was found in the profiles between vehicle co-administered saline and kainate treated animals. Somewhat slower kinetics was observed in the kainate treated compared to the saline treated rats that were also co-administered with tariquidar.
