Table 1.
Subjects characteristics
| Characteristics | Adolescents with CDGP (n = 23) | Normal control (n = 20) |
P-value |
|---|---|---|---|
| Age (years) | 15.1 + 0.67 | 15.1 + 0.72 | 0.9 |
| Weight (kg) | 38.5 + 3.1 | 64.3 + 13.36 | < 0.001* |
| Standing height (cm) | 147.8 + 5.9 | 169.55 + 9.9 | < 0.001* |
| BMI (kg/m2) | 17.6 + 0.9 | 23.4 + 2.2 | < 0.001* |
| Testicular volume (ml) | 2.6 + 0.5 | 11.6 + 2 | < 0.001* |
| Bone age (years) | 12.7 + 0.5 | 15.1 + 0.67 | < 0.001* |
| Bone age delay (years) | 2.3 + 0.4 | - | |
| FSH (iu/ml) | 0.4 + 0.08 | 5.1 + 0. 7 | < 0.001* |
| LH (iu/ml) | 0.2 + 0.06 | 4.3 + 0.7 | < 0.001* |
| Testosterone (ng/ml) | 0.06 + 0.02 | 4.5 + 3.2 | < 0.001* |
| Leptin (ng/ml) | 3.06 + 0.6 | 7.03 + 2.5 | < 0.001* |
| Ghrelin (ng/ml) | 276.4 + 58.9 | 106.5 + 29.6 | < 0.001* |
CDGP: Constitutional delay of growth and puberty; BMI: Body mass index; FSH: Follicle stimulating hormone; LH: Luteinizing hormone; Data are expressed as mean ± standard deviation; *P is significant if < 0.05