Table 2.
Associations between maternal perinatal depression and childhood gastrointestinal infections and childhood lower respiratory infections
| Maternal perinatal depression | ||||||
|---|---|---|---|---|---|---|
| No | Yes | |||||
| Childhood infections | Events | Rate per 10 person-years (95% CI*) |
Events | Rate per 10 person-years (95% CI*) |
Rate difference (95% CI*) |
Unadjusted IRR# (95% CI*) |
| GI infections† | ||||||
| Age (years) | ||||||
| 0-4 | 84999 | 2.44 (2.43-2.46) | 11634 | 3.41 (3.35-3.47) | 0.97 (0.90-1.03) | 1.40 (1.37-1.42) |
| 0-1 | 34928 | 3.71 (3.67-3.75) | 4950 | 5.31 (5.16-5.46) | 1.60 (1.45-1.75) | 1.43 (1.39-1.48) |
| 1-2 | 26845 | 3.02 (2.98-3.06) | 3533 | 4.06 (3.93-4.19) | 1.04 (0.90-1.18) | 1.34 (1.30-1.39) |
| 2-3 | 14289 | 1.69 (1.66-1.72) | 1981 | 2.40 (2.30-2.51) | 0.71 (0.60-0.82) | 1.42 (1.35-1.49) |
| 3-4 | 8937 | 1.11 (1.09-1.13) | 1170 | 1.49 (1.41-1.58) | 0.38 (0.30-0.47) | 1.35 (1.27-1.43) |
| LRTIs‡ | ||||||
| Age (years) | ||||||
| 0-4 | 25143 | 0.72 (0.71-0.73) | 3139 | 0.91 (0.88-0.94) | 0.19 (0.16-0.23) | 1.27 (1.22-1.32) |
| 0-1 | 12202 | 1.28 (1.26-1.31) | 1632 | 1.72 (1.64-1.81) | 0.44 (0.36-0.53) | 1.35 (1.28-1.42) |
| 1-2 | 6530 | 0.73 (0.71-0.75) | 725 | 0.82 (0.76-0.88) | 0.09 (0.03-0.16) | 1.13 (1.05-1.22) |
| 2-3 | 3783 | 0.45 (0.43-0.46) | 454 | 0.55 (0.50-0.60) | 0.10 (0.05-0.15) | 1.23 (1.11-1.35) |
| 3-4 | 2628 | 0.33 (0.31-0.34) | 328 | 0.42 (0.37-0.46) | 0.09 (0.04-0.14) | 1.28 (1.14-1.44) |
* Confidence interval
# Incidence rate ratio
† Gastrointestinal infections
‡ Lower respiratory tract infections