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Modern methods of oral cytology for oral squamous cell carcinoma
| Classification | Analytic method | Markers |
|---|---|---|
| Cytomorphometry | Conventional cytologic diagnosis | Cell morphology |
| Computer-assisted image | Cell morphology | |
| analysis (OralCDx) | ||
| DNA analysis | DNA image cytometry | DNA ploidy, DNA methylation |
| Optical diagnosis | Autofluorescence | Flavin, tryptophan, elastin, |
| collagen (endogenous fluorophores) | ||
| Photodynamic diagnosis | 5-Aminolevulinic acid | |
| Photofrin | ||
| Immunophotodiagnosis antibody targeting | EGFR | |
