Table 6.
Real-time quantitative RT-PCR for selected genes in B6 and TH mice (males, 16 week, n = 5 each group).
| Gene symbol | Gene name | Chr | Near marker | Trait | Tissue | Fold | P |
|---|---|---|---|---|---|---|---|
| 1700009P17Rik | RIKEN cDNA 1700009P17 gene | 1 | D1Mit113 | Tg Chol |
Liver | 0.2 | 0.0007 |
| Ccdc46 | Coiled-coil domain containing 46 | 11 | D11Mit132 | Tg | Liver | 7 | 0.0019 |
| Sirpb1a | Signal-regulatory protein beta 1A | 3 | D3Mit304 | Chol | Adipose tissue | 2.6 | 0.02 |
| Ctrc | Chymotrypsin C (caldecrin) | 4 | D4Mit312 | Glu | Pancreas | 17 | <0.0001 |
| Igfbp2 | Insulin-like growth factor binding protein 2 | 1 | D1Mit215 | FPW | Liver | 0.50 | 0.05 |
| Adipose tissue | 0.1 | <0.0001 | |||||
| Cyp27a1 | Cytochrome P450, family 27, subfamily a, polypeptide 1 | 1 | D1Mit215 | BW FPW |
Adipose tissue | 1.2 | 0.10 |
| Irs1 | Insulin receptor substrate 1 | 1 | D1Mit215 | BW FPW |
Adipose tissue | 0.6 | 0.05 |
| Mogat1 | Monoacylglycerol O-acyltransferase 1 | 1 | D1Mit215 | FPW | Adipose tissue | 0.2 | 0.0002 |
| Usp37 | Ubiquitin specific peptidase 37 | 1 | D1Mit215 | BW FPW |
Adipose tissue | 1.0 | 0.90 |
| Spag5 | Sperm associated antigen 5 | 11 | D11Mit41 | Tg | Muscle | 1.02 | 0.95 |
| Ccl9 | Chemokine (C-C motif) ligand 9 | 11 | D11Mit41 | BW FPW |
Adipose tissue | 2.2 | 0.01 |
| Ccl6 | Chemokine (C-C motif) ligand 6 | 11 | D11Mit41 | BW FPW |
Adipose tissue | 1.4 | 0.20 |
| Ccl3 | Chemokine (C-C motif) ligand 3 | 11 | D11Mit41 | BW FPW |
Adipose tissue | 5.5 | <0.0001 |
| Msi2 | Musashi homolog 2 (Drosophila) | 11 | D11Mit41 | Tg | Muscle | 1.03 | 0.75 |
| Agtr1b | Angiotensin II receptor, type 1b | 3 | D3Mit304 | Tg | Muscle | 1.11 | 0.85 |
| Pik3ca | Phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 3 | D3Mit304 | Tg | Muscle | 0.91 | 0.24 |
| Ccdc39 | Coiled-coil domain containing 39 | 3 | D3Mit304 | Tg | Muscle | 0.66 | 0.40 |
| Ccdc79 | Coiled-coil domain containing 79 | 8 | D8Mit242 | Tg | Muscle | 0.59 | 0.40 |
| Apoa2 | Apolipoprotein A-II | 1 | D1Mit113 | Tg Chol |
Liver | 1.07 | 0.08 |
| Insig2 | Insulin induced gene 2 | 1 | D1Mit113 | Tg Chol |
Muscle | 0.95 | 0.73 |
| Zfp69 | Zinc finger protein 69 | 4 | D4Mit312 | Glu | Adipose tissue | 2.2 | 0.03 |
Chr, chromosome; Fold, the fold change in TH vs. B6 (TH/B6); Tg, triglyceride; Chol, cholesterol; Glu, glucose; FPW, fat pad weight; BW, body weight.