Table 2.
Cardiac enriched miRNAs
| miRNA transcript | Location | EM-s | HT-s | Fold Difference |
|---|---|---|---|---|
| miRNA|ENSGALT00000028994|5p~|gga-mir-133a-1|sense # | chr2:105670407-105670428|- | 0 ± 0 | 9 ± 1.3 | inf |
| miRNA|ENSGALT00000028999|3p|gga-mir-1a-1|sense | chr20:8107876-8107896|- | 0 ± 0 | 23 ± 6.9 | inf |
| miRNA|ENSGALT00000029007|5p~|gga-mir-133c|sense # | chr23:4664062-4664083|+ | 0 ± 0 | 8 ± 2.9 | inf |
| miRNA|ENSGALT00000035316|5p|gga-mir-499|sense # | chr20:2599386-2599408|- | 2.8 ± 1.3 | 2542.5 ± 574 | 906 |
| miRNA|ENSGALT00000035316|3p~|gga-mir-499|sense # | chr20:2599348-2599370|- | 15.5 ± 1.1 | 3048.4 ± 318.2 | 196 |
| miRNA|ENSGALT00000029007|3p|gga-mir-133c|sense # | chr23:4664099-4664120|+ | 2.8 ± 1.3 | 496.9 ± 44.9 | 177 |
| miRNA|ENSGALT00000029006|5p~|gga-mir-1b|sense | chr23:4663916-4663936|+ | 1.7 ± 1.1 | 142.9 ± 22.7 | 83 |
| miRNA|ENSGALT00000028999|5p~|gga-mir-1a-1|sense | chr20:8107838-8107858|+ | 35.4 ± 20.4 | 2366.1 ± 777.2 | 67 |
| miRNA|ENSGALT00000029006|3p|gga-mir-1b|sense | chr23:4663953-4663973|+ | 91.1 ± 24.2 | 6086.5 ± 1328.3 | 67 |
| miRNA|ENSGALT00000042439|5p||sense | chr4:2151195-2151215|+ | 1.4 ± 2 | 32.5 ± 0.4 | 23 |
| miRNA|ENSGALT00000042439|3p||sense # | chr4:2151238-2151260|+ | 30.2 ± 6.1 | 1277.3 ± 123.2 | 42 |
| miRNA|ENSGALT00000035276|3p|gga-mir-490|sense | chr1:59948716-59948737|- | 45.3 ± 12.6 | 1447.5 ± 231.3 | 32 |
| miRNA|ENSGALT00000042468|5p|gga-mir-1773|sense | chr20:8109147-8109169|+ | 1.1 ± 0.2 | 25.5 ± 3.8 | 23 |
| miRNA|ENSGALT00000042438|3p|gga-mir-1799|sense | chr5:42365992-42366012|+ | 8.6 ± 6.9 | 130.5 ± 0.5 | 15 |
| miRNA|ENSGALT00000035276|5p~|gga-mir-490|sense | chr1:59948755-59948776|- | 13.8 ± 2.1 | 228.3 ± 47.4 | 17 |
| miRNA|ENSGALT00000042432|3p~|sense | chr1:104486649-104486675|- | 8.2 ± 4.6 | 84.6 ± 5.7 | 10 |
| miRNA|ENSGALT00000029028|3p|gga-mir-133b|sense # | chr3:110384948-110384968|- | 93 ± 21.6 | 866.5 ± 52.1 | 9.3 |
| miRNA|ENSGALT00000042246|3p~|gga-mir-1731|sense | chr12:10938277-10938299|- | 1.7 ± 1.1 | 15 ± 1.6 | 8.8 |
| miRNA|ENSGALT00000042411|5p|gga-mir-1434|sense | chr28:1055205-1055224|+ | 26.5 ± 11.3 | 204.5 ± 18.6 | 7.7 |
| miRNA|ENSGALT00000035271|3p|gga-mir-193b|sense | chr14:759503-759526|+ | 31.8 ± 0.3 | 213.2 ± 26 | 6.7 |
| miRNA|ENSGALT00000042289|5p|gga-mir-1747|sense | chr2:62758752-62758773|- | 2.1 ± 1.2 | 12.5 ± 0.6 | 6.1 |
| miRNA|ENSGALT00000028974|5p|gga-mir-146a|sense | chr13:7555655-7555676|- | 10.6 ± 4.2 | 60.6 ± 8.3 | 5.7 |
| miRNA|ENSGALT00000028997|5p|gga-mir-30d|sense # | chr2:148337300-148337321|- | 1452 ± 39.6 | 7275.3 ± 46.5 | 5.0 |
| miRNA|ENSGALT00000042432|5p||sense | chr1:104486710-104486736|- | 915.9 ± 102.7 | 3702.3 ± 152.3 | 4.0 |
| miRNA|ENSGALT00000028990|3p~|gga-mir-138-1|sense | chr2:40745167-40745183|- | 9.4 ± 2.4 | 33.5 ± 1 | 3.6 |
| miRNA|ENSGALT00000028998|5p|gga-mir-30b|sense | chr2:148331648-148331669|- | 461.2 ± 63 | 1638.4 ± 129.7 | 3.6 |
| miRNA|ENSGALT00000029030|3p|gga-mir-223|sense | chr4:233007-233027|+ | 2759.8 ± 88 | 9608.1 ± 564.1 | 3.5 |
| miRNA|ENSGALT00000042472|5p|gga-mir-1677|sense # | chr3:76659772-76659792|+ | 219.8 ± 31.9 | 725.3 ± 80.2 | 3.3 |
| miRNA|ENSGALT00000028951|5p|gga-mir-125b|sense # | chr1:102457663-102457684|+ | 5255.7 ± 209.1 | 15151.5 ± 1241 | 2.9 |
| miRNA|ENSGALT00000035272|3p|gga-mir-181a-1|sense | chr8:2001620-2001641|+ | 154.6 ± 49.6 | 424.6 ± 8.1 | 2.7 |
| miRNA|ENSGALT00000029026|5p|gga-mir-30a|sense # | chr3:85102244-85102265|+ | 898.4 ± 20.4 | 2238.4 ± 52.7 | 2.5 |
| miRNA|ENSGALT00000035333|3p|gga-mir-144|sense | chr19:5824134-5824155|- | 79.4 ± 4.2 | 187.5 ± 8.9 | 2.4 |
| miRNA|ENSGALT00000029015|5p|gga-let-7k|sense | chr26:1442955-1442976|- | 11.8 ± 1 | 25.5 ± 3.8 | 2.2 |
| miRNA|ENSGALT00000028983|5p|gga-mir-126|sense # | chr17:8431792-8431812|- | 1310.7 ± 123.6 | 2561 ± 161.5 | 2.0 |
| miRNA|ENSGALT00000029008|5p|gga-mir-30e|sense | chr23:5248432-5248450|+ | 1382.7 _ 30.5 | 2630.2 ± 3.1 | 1.9 |
| miRNA|ENSGALT00000042329|3p~|gga-mir-1811|sense | chr4:58651749-58651768|+ | 60.9 _ 6 | 105.5 ± 4 | 1.7 |
| miRNA|ENSGALT00000028959|3p~|gga-mir-18a|sense | chr1:152248637-152248658|- | 49.1 _ 0.3 | 82.5 ± 2.8 | 1.7 |
Table of significantly cardiac enriched miRNA transcripts. Indicated are transcript name (EnsemblTranscript | 5p/3p | miRNA name | (anti)sense), genomic location, average expression values ± SD and the fold difference between samples. The ' ~' indicates miRNA transcripts for which the genomic positions were not present in the Ensembl database and thus were inferred from the complementary position of the hairpin structure. # indicates the difference in expression level was confirmed by qPCR.