. Author manuscript; available in PMC: 2011 Feb 1.

Published in final edited form as: Pediatr Surg Int. 2011 Feb;27(2):137–143. doi: 10.1007/s00383-010-2786-z

Table 2.

Histological scores of implanted internal anal sphincter constructs

	Morphology score (0–4)	Degeneration score (0–4)	Blood vessel score (0–2)	Total histological score (0–10)	Blood vessels per HPF	Muscle fiber diameter (μm)
No growth factor	1.2 ± 0.8	2.0 ± 0.7	0.2 ± 0.4	3.4 ± 1.8	1.2 ± 0.4	20 ± 5.0
FGF	3.0 ± 0.7	3.4 ± 0.6	1.6 ± 0.5	8.0 ± 1.6	5.6 ± 2.0^*	32.0 ± 5.7
VEGF	3.5 ± 0.6^{^}	3.3 ± 0.5	2.0 ± 0.0^{^}	8.8 ± 0.5^{^}	4.6 ± 1.0^*	31.4 ± 1.0
PDGF	2.5 ± 1.0	3.3 ± 1.0	1.8 ± 0.5	7.3 ± 1.7	4.7 ± 1.3^*	33.8 ± 6.3^*

Results expressed as mean ± standard deviation.

p < 0.05 by one-way ANOVA and Tukey's post-test compared to no growth factor.

^{^}

p < 0.05 by Kruskal-Wallis test and Dunn's post-test compared to no growth factor

HPF high-powered field