Table 2.
The specific effect of motion-affected IDIFs on outcome of tracer kinetic analysis. Mean V T differences (mean ± SD%) over different anatomic regions derived from original (no motion) simulated PET scans in combination with IDIFs extracted from motion-affected simulated PET scans
| Motion | V T error (%) [11C]flumazenil | V T error (%) (R)-[11C]verapamil | |
|---|---|---|---|
| Translational (mm) | 1 | 1.0 ± 0.0 | 2.7 ± 0.0 |
| 2 | 1.9 ± 0.0 | 5.4 ± 0.0 | |
| 3 | 2.7 ± 0.0 | 7.8 ± 0.1 | |
| 4 | 3.7 ± 0.0 | 10.2 ± 0.1 | |
| 5 | 4.6 ± 0.0 | 12.4 ± 0.1 | |
| 6 | 5.6 ± 0.0 | 14.6 ± 0.1 | |
| 10 | 11.0 ± 0.0 | 23.2 ± 0.1 | |
| 15 | 30.2 ± 0.0 | 32.8 ± 0.2 | |
| 20 | 30.2 ± 0.0 | 40.6 ± 0.2 | |
| Rotation (deg) | 1 | 0.1 ± 0.0 | 0.1 ± 0.0 |
| 3 | 1.7 ± 0.0 | 0.6 ± 0.0 | |
| 4 | 3.0 ± 0.0 | 1.4 ± 0.0 | |
| 6 | 6.4 ± 0.0 | 3.6 ± 0.0 | |
| 7 | 8.5 ± 0.0 | 5.2 ± 0.0 | |
| 8 | 10.8 ± 0.0 | 7.1 ± 0.0 | |
| 10 | 15.5 ± 0.0 | 11.2 ± 0.1 | |
| 12 | 20.4 ± 0.0 | 15.8 ± 0.1 | |
| 15 | 27.5 ± 0.0 | 22.5 ± 0.1 |