Table 2.
Lipid profile | Period | Control | Ethanolic extract | Tolbutamide |
---|---|---|---|---|
TG | 0 day | 84.46 ± 1.50 | 82.28 ± 1.65 | 85.32 ± 1.78 |
7 days | 80.32 ± 2.08 | 77.25 ± 1.82*** | 76.21 ± 1.63*** | |
14 days | 81.04 ± 1.70 | 71.02 ± 1.46*** | 69.35 ± 1.14*** | |
21 days | 80.61 ± 1.94 | 64.70 ± 2.01*** | 62.03 ± 1.46*** | |
TCH | 0 day | 78.23 ± 1.75 | 79.06 ± 1.89 | 76.14 ± 1.23 |
7 days | 79.13 ± 0.71 | 73.72 ± 1.06*** | 70.09 ± 1.37*** | |
14 days | 77.65 ± 1.30 | 69.08 ± 1.57*** | 65.43 ± 1.11*** | |
21 days | 76.45 ± 0.90 | 62.56 ± 1.78*** | 58.22 ± 1.93 | |
HDL | 0 day | 22.18 ± 1.01 | 18.21 ± 1.19 | 21.65 ± 1.08 |
7 days | 21.06 ± 1.82 | 19.42 ± 1.42NS | 22.78 ± 0.98NS | |
14 days | 22.47 ± 1.13 | 20.22 ± 1.53* | 24.61 ± 1.02*** | |
21 days | 39.16 ± 1.32 | 21.52 ± 1.23*** | 26.52 ± 1.36*** | |
LDL | 0 day | 42.01 ± 1.04 | 44.40 ± 2.16 | 42.67 ± 1.72 |
7 days | 38.98 ± 1.77 | 38.85 ± 1.89*** | 34.25 ± 1.53*** | |
14 days | 39.41 ± 1.53 | 34.66 ± 2.31*** | 29.72 ± 1.19*** | |
21 days | 16.98 ± 1.50 | 28.70 ± 1.87*** | 25.92 ± 1.02*** | |
VLDL | 0 day | 16.89 ± 1.50 | 16.45 ± 1.42 | 17.81 ± 1.24 |
7 days | 16.06 ± 1.81 | 15.45 ± 0.92NS | 15.87 ± 1.17NS | |
14 days | 16.20 ± 1.62 | 14.20 ± 1.40* | 13.93 ± 1.34* | |
21 days | 16.12 ± 1.60 | 12.94 ± 0.74*** | 12.36 ± 1.35*** |
Values are mean ± SD, n = 6 in each group. NS = nonsignificant
P < 0.05
**P < 0.01
P < 0.001 when compared with the vehicle-treated group