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. 2011 Jan 17;208(1):13–21. doi: 10.1084/jem.20100762

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© 2011 Björkström et al.

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Figure 1. — Increase in CD56^dim NK cells in human hantavirus infection. PBMCs from patients with acute hantavirus infection were analyzed by flow cytometry. (a and b) Absolute numbers of lymphocytes (a) and NK cells (b) at days 5 and 60 after symptom debut. (c) Relative changes of total lymphocytes and NK cells from days 5–60 after symptom debut (mean ± SEM). (d) Definition of CD56^brightCD16⁻ (i), CD56^brightCD16⁺ (ii), CD56^dimCD16⁺ (iii), and CD56⁻CD16⁺ (iv) NK cells by flow cytometry from one representative patient with acute hantavirus infection. Cells were gated on the CD3⁻CD4⁻CD14⁻CD19⁻ population within the single cell lymphocyte gate. (e) Absolute numbers of the different NK cell subsets at days 5 and 60. For a–e, n = 16. *, P < 0.05; **, P < 0.01; ***, P < 0.0001, paired Student’s t test.