Circulating IGF-I and corticosterone levels of fed (open bars) or fasted (filled bars) (A and B, respectively, left) and SST-intact (open bars) and SST-knockout (SST-KO; filled bars) (A and B, respectively, right) male and female mice. IGF-I and corticosterone values are represented as means ± SE (ng/ml; n = 4–10 mice/treatment-genotype/sex) and were determined by commercial RIA or ELISA kits, respectively. Symbols (*P < 0.05, **P < 0.01) indicate differences between fed and fasted mice or between SST-intact and SST-KO mice within sex.