Table 1.
Prepace Intact (n = 5) | Postpace Intact (n = 5) | Prepace DnX (n = 5) | Postpace DnX(n = 5) | |
---|---|---|---|---|
Weight, kg | 3.25 ± 0.07 | 3.32 ± 0.05 | 3.50 ± 0.13 | 3.61 ± 0.12 |
HR, beats/min | 213 ± 8 | 233 ± 11 | 235 ± 5 | 226 ± 13 |
MAP, mmHg | 69.6 ± 3.7 | 62.5 ± 4.4* | 62.2 ± 4.6 | 59.9 ± 4.9 |
LVEDD, mm | 15.9 ± 0.7 | 17.0 ± 1.0 | 15.3 ± 0.6 | 17.1 ± 0.5 |
LVESD, mm | 10.3 ± 0.4 | 14.1 ± 1.0* | 9.6 ± 0.4 | 13.9 ± 0.5* |
FS, % | 35.6 ± 0.7 | 17.1 ± 1.0* | 37.1 ± 0.7 | 18.6 ± 1.0* |
EF, % | 68.8 ± 0.9 | 38.6 ± 2.1* | 70.9 ± 0.8 | 41.5 ± 1.9* |
Values are mean ± SE; n = no. of rabbits. HF, heart failure; DnX, (left) unilateral renal denervation; HR, heart rate; MAP, mean arterial pressure; LVEDD, left ventricular end diastolic diameter; LVESD, left ventricular end systolic diameter; FS, fractional shortening; EF, ejection fraction.
P < 0.05 vs. respective sham group.