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Antioxidant tempol decreases age-related increase in plasma 8-isoprostane levels in old rats. 8-Isoprostane in plasma was measured using an EIA-based kit assay (details in methods). Results are means ± SE (n = 6–8 rats in each group). ***Significantly different from adult rats at P < 0.001. #Significantly different from old rats at P < 0.05 (1-way ANOVA followed by Newman-Keuls post hoc test).
