Table 3.

Membrane actions of 2-APB and DPBA on in situ vascular smooth muscle cells

	2-APB (100 μM)			DPBA (100 μM)
	Control	In treatment	Change, %	Control	In treatment	Change, %
SMA
Input resistance, MΩ	584 ± 106	4,164 ± 400†	908 ± 137	571 ± 114	4,937 ± 741†	982 ± 107
n		13			12
Input conductance, nS	2.24 ± 0.26	0.24 ± 0.033†	−86 ± 2.1	2.6 ± 0.43	0.26 ± 0.43*	−88 ± 1.4
n		13			12
Input capacitance, pF	55.6 ± 9.5	6.01 ± 0.29†	−89.2 ± 3.1	71.5 ± 22.5	5.82 ± 0.19†	−91.1 ± 1.2
		11			10
BA
Input resistance, MΩ	316 ± 30	1,835 ± 219†	631 ± 177	683 ± 92	3,703 ± 367†	559 ± 141
n		6			8
Input conductance, nS	3.89 ± 1.0	0.57 ± 0.076†	−80 ± 6.1	1.7 ± 0.26	0.27 ± 0.02†	−81 ± 3.7
n		6			8
Input capacitance, pF	91.4 ± 26.8	6.7 ± 0.61†	−90.4 ± 2.9	116.2 ± 41.7	7.12 ± 0.7†	−89.5 ± 3.3
n		4			5
MA
Input resistance, MΩ	360 ± 114	2,967 ± 644†	884 ± 238	380 ± 81	3,336 ± 479†	1,190 ± 479
n		6			12
Input conductance, nS	4.31 ± 1.0	0.44 ± 0.15*	−87 ± 3.2	4.7 ± 1.2	0.31 ± 0.04*	−87 ± 3.4
n		6			12
Input capacitance, pF	281 ± 131	9.52 ± 1.29†	−81.8 ± 9.3	193 ± 61.3	9.58 ± 0.9†	−89.8 ± 4.29
n		7			7

Values are means ± SE; n, number of cells. Input resistance and input conductance were measured between −60 and −40 mV. Input capacitance was measured by a step from −40 to −100 mV. 2-APB, 2-aminoethoxydiphenyl borate; DPBA, diphenylboronic anhydride.

^*P < 0.05 and

^†P < 0.01, comparison between the control and treatment (paired t-test).