Fig. 2.
AICAR stimulates HO-1 protein and mRNA expression in human aortic ECs. A: time course of HO-1 protein expression after the administration of AICAR (0.5 mM). B: time course of HO-1 mRNA expression after the administration of AICAR (0.5 mM). HO-1 protein and mRNA expression were quantified by scanning densitometry, normalized with respect to β-actin or 18S rRNA, respectively, and expressed relative to that of control, untreated cells. Results are means ± SE of 3 experiments. *Statistically significant effect of AICAR.