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AICAR stimulates HO-1 protein expression in blood vessels. HO-1 protein expression in rat carotid arteries treated with an empty gel or AICAR (1 mg)-containing gel for 24 h is shown. HO-1 protein expression was quantified by scanning densitometry, normalized with respect to β-actin, and expressed relative to that of control, untreated cells. Results are means ± SE of 4 measurements. *Statistically significant effect of AICAR.
