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Aortic reactivity. Acetylcholine-evoked vasorelaxation (A), l-NMMA-evoked vasocontraction after precontraction using phenylephrine (PE; B), and sodium-nitroprusside evoked vasorelaxation (C) were similar among WT and CIRKO mice 14 days after the sham or TAC procedure. Results are means ± SE from 2 aortic segments/mouse from 14 WT-sham, 14 WT-TAC, 12 CIRKO-sham, and 11 CIRKO-TAC mice.
