Fig. 4.

No discernible role of Na⁺-K⁺-ATPase and inwardly rectifying K⁺ channels as targets for EDHF in vasodilations in the human coronary microcirculation. A and B: neither ouabain alone (10⁻⁴ M, n = 5; A) nor the combination of ouabain and BaCl₂ (3 × 10⁻⁵ M, n = 5; B) had an inhibitory effect on EDHF-mediated response to bradykinin (BK; P = NS). C: there was no correlation between the magnitudes of maximal K⁺-induced vasodilation and EDHF-mediated vasodilation to 10⁻⁷ M BK (n = 27). Values are means ± SE.