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. 2010 Nov 5;300(1):H57–H63. doi: 10.1152/ajpheart.00225.2010

Fig. 7.

Fig. 7.

Expression of dn-PTP1B rescues cells from the suppression of PKG induced by a NO donor. Cells were cultured for 24 h in the presence of serum-free medium containing control adenovirus expressing EGFP or adenovirus expressing dn-PTP1B (C215S-PTP1B) at a multiplicity of infection of 5–10 followed by a 24-h incubation in serum-free medium and 24 h in serum-free medium supplemented with 100 μM DETA-NO plus control virus or virus expressing dn-PTP1B. A: Western blots from a representative experiment. B: summary of results (means ± SE) from 3 experiments, normalized to α-actin. *P < 0.05 compared with the control.