Fig. 4.

Nonpressor doses of ANG II attenuate CBF responses. A: systolic blood pressure measured by tail-cuff plethysmography during infusion of nonpressor doses of ANG II (200 ng·kg⁻¹·min⁻¹; n = 5/group). B: MAP measured through a femoral catheter during the CBF experiments in mice infused with ANG II (200 or 600 ng·kg⁻¹·min⁻¹) for 14 days. C–G: ANG II infusion (200 and 600 ng·kg⁻¹·min⁻¹) attenuate CBF responses to whisker stimulation, ACh, bradykinin, A-23197, but not adenosine. *P < 0.05 from vehicle; #P < 0.05 from ANG II-200 and vehicle (ANOVA and Tukey's test; n = 5/group).