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A peptide inhibitor of NADPH oxidase counteracts the cerebrovascular dysfunction induced by ANG II. A–D: gp91ds-tat (gp91; 1 μM), but not its scrambled control (s-gp91; 1 μM), reverses the effect of ANG II on CBF responses to whisker stimulation, A-23187, and bradykinin. E: CBF response to adenosine is not affected. *P < 0.05 from saline and gp91; n = 5/group.
