Table 7.
Components of the primary end point reached in the JUPITER study
End point | Rosuvastatin group | Placebo group | Hazard ratio | 95% CI | P value |
---|---|---|---|---|---|
Primary end point | 142 | 251 | 0.56 | 0.46–0.69 | <0.00001 |
Nonfatal MI | 22 | 62 | 0.35 | 0.22–0.58 | <0.00001 |
Any MI | 31 | 68 | 0.46 | 0.30–0.70 | <0.0002 |
Nonfatal stroke | 30 | 58 | 0.52 | 0.33–0.80 | 0.003 |
Any stroke | 33 | 64 | 0.52 | 0.34–0.79 | 0.002 |
Revascularization or Unstable angina | 76 | 143 | 0.53 | 0.40–0.70 | <0.00001 |
MI, stroke, CV death | 83 | 157 | 0.53 | 0.40–0.69 | <0.00001 |
Total mortality | 198 | 247 | 0.80 | 0.67–0.97 | 0.02 |
CV death (verified) | 35 | 43 | 0.82 | 0.52–1.27 | 0.37 |
Sudden death | 16 | 25 | 0.64 | 0.34–1.20 | 0.16 |
Abbreviations: CI, confidence interval; CV, cardiovascular; MI, myocardial infarction.