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. Author manuscript; available in PMC: 2011 Dec 17.
Published in final edited form as: J Mol Biol. 2010 Oct 8;404(5):751–772. doi: 10.1016/j.jmb.2010.09.009

Figure 5.

Figure 5

Structure of [ΨCD]2 determined by NMR. (a,b) Orthogonal views of the ensemble of 20 structures calculated with Cyana showing the degree of convergence and overall shape and asymmetry of the dimer. The 5′- and 3′-terminal residues are labeled, along with the position of the experimentally unrestrained U319 residue. Carbon atoms of the two molecules of the dimer are colored gray and green. (c,d) Stereoviews showing (c) the structure of the A-minor K-turn and it’s proximity to the kissing interface, and (d) stacking of the A353 and A354 residues between the stems of SL-C and SL-D. (e) View showing one molecule of the symmetrical dimer. Adenosines that bridge SL-C and SL-D (blue) and residues that make intermolecular kissing contacts (red) are highlighted.