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TG-associated genes identified by various methodologies involved in HTG
| Locus | Identified by GWAS of HTG | Replication of population-based TG-associated loci | HTG-causing rare variants | Mouse models of HTG | Family based and linkage studies |
|---|---|---|---|---|---|
| APOA5 | X | X | X | ||
| GCKR | X | X | |||
| LPL | X | X | X | ||
| APOB | X | X | |||
| APOE | X | X | X | ||
| ANGPTL3 | X | ||||
| MLXIPL | X | ||||
| TRIB1 | X | ||||
| NCAN | X | ||||
| GALNT2 | X | ||||
| LIPC | X | ||||
| APOC2 | X | X | |||
| GPIHBP1 | X | X | |||
| LMF1 | X | X | |||
| USF1 | X |
GWAS, genome-wide association study; HTG, hypertriglyceridemia; TG, triglyceride; X, the locus was identified.
