Fig. 7.

OA and LA alleviate ER stress response caused by thapsigargin. A: Effects of OA (200 μM) and LA (200 μM) on 2 μM thapsigargin-induced LOX-1 upregulation. LOX-1 expression 24 h after thapsigargin treatment was quantified by real-time PCR and normalized relative to 18S rRNA. Data are expressed as means ± SE of four independent experiments. * P < 0.05 versus thapsigargin. B: ER stress markers in THP-1 cells stimulated with thapsigargin in the presence or absence of OA and LA for 3 h were analyzed by Western blot.