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Ebelactone B inhibition of EL, HL, and LPL in cell-based assays. Cell-based assays with increasing PLA1 substrate concentrations, using HEK293 untransfected control cells (A) or transfected HEK293 expressing either murine EL (B), hHL (C), or hLPL (D) were run in the absence or presence of the nonselective esterase inhibitor ebelactone B (10 µM). These assays, run in triplicate for 30 min, represent one of three different experiments yielding identical results.
