FIG. 6.
Coexposure to TCE and HgCl2 increased autoantibody production. Sera obtained at 4, 6, or 8 weeks from individual mice treated with water alone (controls), water with TCE, and/or HgCl2 were evaluated for IgG1 and IgG2a ANA. The ANA results are presented as the inverse of the highest dilution that provided a positive score. These results duplicate those found in an earlier analysis conducted with fewer sera but a wider dilution range. Levels of total IgG1 and IgG2a in the sera collected at the 8-week time point are also shown. *Statistically different from results in control mice.