Table 1.
Toll-like receptor | Ligand |
TLR1 | Lipopeptides |
TLR2 | Lipoprotein, lipoteichoic acid, others |
TLR3 | Double-stranded RNA |
TLR4 | Lipopolysaccharide (LPS) |
TLR5 | Flagellin |
TLR6 | Lipoprotein, lipoteichoic acid, others |
TLR7 | Viral RNA |
TLR8 | Viral RNA |
TLR9 | Unmethylated CpG-containing DNA |
TLR10 | Unknown |
TLR11 | Profillin |
There are currently over ten known Toll-like receptors that bind microbial associated molecular patterns (MAMPs) from bacteria, fungi and viruses.