Table 1. Circulating levels (ng/ml) of pituitary (regulated) hormones, in AOiGHD and Controls.
Males* | Females | |||
Control | AOiGHD | Control | AOiGHD | |
Prolactin | 1.75±0.27 | 1.6±0.13 | 43.11±6.8 | 34.11±3.25 |
Testosterone | 7.42±2.78 | 5.42±1.76 | ND | ND |
Thyroid hormone (T4) | 5.42±0.22 | 5.51±0.13 | 6.78±0.24 | 7.64±0.45 |
Corticosterone fed | 1.38±0.25 | 1.41±0.25 | 2.86±0.85 | 3.86±0.59 |
Corticosterone fasted | 34±2.09 | 33.8±3.22 | 33.33±5.7 | 32.38±4.32 |
*Values shown for males are from LF- fed mice described in Fig 3 (from t0 samples of GTT or ITT), while female values are from chow fed mice. Hormone levels were compared between genotypes from blood samples taken at the same age, from 2–6 months post DT treatment (n = 6–12 samples/measurement).