Table 2.
Genes Dysregulated in EBV-positive AGS Cells
| Gene Name | Gene Symbol | Fold Change* |
|---|---|---|
| Downregulated Genes | ||
| basic leucine-zipper transcription factor, ATF-like | BATF | -38 |
| cyclooxygenase-2 | COX2 | -35 |
| bone morphogenic protein-4 | BMP4 | -32 |
| intercellular adhesion molecule-1 | ICAM1 | -22 |
| trefoil factor-1 | TFF1 | -21 |
| inhibitor of DNA binding-2 | ID2 | -14 |
| heat shock protein-70 | HSP70 | -10 |
| cyclin-dependent kinase-2 | CDK2 | -9 |
| cyclin-D1 | CCND1 | -9 |
| hypoxia inducible factor-1A | HIF1A | -9 |
| breast cancer-1 | BRCA1 | -7 |
| nucleostemin | NU | -7 |
| cyclin-dependent kinase inhibitor-2A | CDKN2A/p16 | -6 |
| inhibitor of DNA binding-4 | ID4 | -6 |
| engrailed-1 | EN1 | -5 |
| ATP-binding cassette, sub-family B, member 1 | ABCB1 | -3 |
| MDM2 p53 binding protein | MDM2 | -3 |
| Upregulated Genes | ||
| insulin-like growth factor binding protein-3 | IGFBP3 | +40 |
| tumor necrosis factor receptor-associated factor-1 | TRAF1 | +20 |
| transmembrane prostate androgen-induced protein | TMEPAI | +10 |
| tumor necrosis factor, superfamily member-10 | TNFSF10 | +8 |
| B cell lymphoma-2-like-1 | BCL2L1 | +7 |
| baculoviral IAP repeat containing-3 | BIRC3 | +5 |
| hexokinase-1 | HK1 | +5 |
| FOS-like antigen-1 | FOSL1 | +3 |
*Listed are genes dysregulated by >2-fold using rtPCR