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. 2011 Jan 7;8:1. doi: 10.1186/1742-4933-8-1

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Copyright ©2011 McDonald et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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ILFs from aged mice have an aberrant cellular composition. The cellular composition of ILFs isolated from aged and young mice was evaluated using multi-color flow cytometry. ILF cellular populations from aged mice had a significantly decreased population of B-lymphocytes (panel a) and a significantly increased population of T-lymphocytes (panel b). The population of antigen presenting cells (APCs) was not significantly different between aged and young mice. n = 3 or more mice in each group. * = p < 0.05.