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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Dev Dyn. 2010 Oct 19;239(12):3226–3234. doi: 10.1002/dvdy.22458

Figure 2. Effects of wild-type and kinase dead EphA3 on EMT.

Figure 2

(A&B) Wild-type EphA3, kinase dead EphA3, or control GFP adenoviruses were injected into the lumen of the chick heart tube at stage 10–12. AV cushions and ventricles were harvested and subjected to collagen gel assay. Kinase dead EphA3 virus significantly inhibited the numbers of transformed cells. Three independent experiments were conducted and analyzed as described in Figure 1B. See Table S1 for complete results. (C) 293T cells were infected with adenovirus carrying either wild-type or kinase dead EphA3. Cell lysates were immunoprecipitated with anti-EphA3 and subjected to in vitro kinase assay.