Table 1.
Baseline Subject Characteristics
| Serum arylesterase activity | ||||
|---|---|---|---|---|
| Variable | Total | <121 μM/min/mL (n=622) | ≥121 μM/min/mL (n=138) | P-value |
| Age (years) | 64 ±11 | 64 ±11 | 64 ±11 | 0.346 |
| Male (%) | 74 | 74 | 73 | 0.800 |
| Diabetes mellitus (%) | 39 | 40 | 35 | 0.289 |
| Hypertension (%) | 72 | 71 | 76 | 0.270 |
| Ischemic etiology (%) | 68 | 67 | 73 | 0.192 |
| LDL cholesterol (mg/dL) | 94 (75, 116) | 93 (74, 113) | 108 (84, 129) | <0.001 |
| HDL cholesterol (mg/dL) | 32 (26, 38) | 31 (26, 36) | 36 (30, 45) | <0.001 |
| BNP (mg/dL) | 193 (86, 481) | 212 (94, 505) | 133 (67, 351) | <0.001 |
| LV Ejection Fraction (%u) | 35 (30, 45) | 35 (30, 45) | 40 (30, 45) | 0.110 |
| CrCl (ml/min/1.73m2) | 100 ± 41 | 100± 42 | 101±36 | 0.652 |
| Baseline Medications: | ||||
| Aspirin (%) | 73 | 72 | 80 | 0.075 |
| Statins (%) | 62 | 61 | 68 | 0.149 |
| Diuretics (%) | 39 | 40 | 38 | 0.704 |
| ACE inhibitors (%) | 63 | 64 | 61 | 0.579 |
| Beta-blockers (%) | 67 | 67 | 67 | 0.983 |
Values expressed in mean ± standard deviation or median (interquartile range). Abbreviations: LV = left ventricle; LDL = low-density lipoprotein; HDL = high-density lipoprotein; BNP = B-type natriuretic peptide; CrCl = creatinine clearance; ACE = angiotensin converting enzyme