Table 1.

Kinetics of circulating blood cell populations using CBC and flow cytometry. Data are shown as median values with interquartile range. P_adj values are from exact paired Wilcoxon test, adjusted for multiple comparisons over time

Cell types	Baseline	Day 14	Day 28	Day 42
WBCs, 109/L	5.80 [4.80,8.23]	4.45 [3.38,6.40]	3.20 [2.65,3.75]	3.40 [3.15,4.85]
	n=34	n=32	n=27	n=23
Padj value	N/A	<0.0001	<0.0001	<0.0001
Lymphocytes, 109/L	1.25 [0.95,1.55]	1.09 [0.81,1.44]	0.99 [0.76,1.27]	0.95 [0.83,1.50]
	n=34	n=32	n=27	n=23
Padj value	N/A	0.017	0.0016	0.014
Hemoglobin, g/dL	13.7 [12.0,14.7]	14.1 [12.8,15.6]	13.9 [12.8,14.9]	12.9 [11.9,13.4]
	n=34	n=32	n=27	n=34
Padj value	N/A	0.0003	0.52	0.0056
Monocytes, 109/L	0.39 [0.31,0.57]	0.21 [0.13,0.26]	0.19 [0.15,0.23]	0.28 [0.23,0.40]
	n=34	n=32	n=27	n=23
Padj value	N/A	<0.0001	<0.0001	0.042
Platelets, 109/L	188 [148,238]	128 [86,206]	105 [75,136]	160 [126,219]
	n=34	n=32	n=27	n=23
Padj value	N/A	<0.0001	<0.0001	0.071
Neutrophils, 109/L	3.83 [3.03,5.46]	2.84 [2.08,3.97]	1.69 [1.34,2.06]	1.88 [1.69,2.99]
	n=34	n=32	n=27	n=23
Padj value	N/A	<0.0001	<0.0001	<0.0001
VEGFR2+CD34+CD133+cells, (% of WBCs)	0.060 [0.030,0.120]	0.030 [0.020,0.045]	0.080 [0.025,0.110]	N/A
	n=9	n=8	n=7