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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Surg Oncol Clin N Am. 2011 Jan;20(1):79–103. doi: 10.1016/j.soc.2010.09.008

Figure 2. Schematic of hyperthermic isolated limb perfusion.

Figure 2

The affected limb’s main artery and vein are surgically exposed and openly cannulated. Warming blankets maintain hyperthermia and temperature is monitored with temperature probes. The tourniquet is applied proximally and the melphalan chemotherapy perfusate is circulated with heated, high-flow membrane oxygenator to maintain acid-base status of the limb. Reproduced with permission from Muchmore et al., Surg Oncol Clin N Am. 2008 Oct;17(4):709–30, vii.