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. Author manuscript; available in PMC: 2011 Nov 16.
Published in final edited form as: Cancer Cell. 2010 Nov 16;18(5):472–484. doi: 10.1016/j.ccr.2010.10.019

Figure 2. Dual inactivation of FoxO and Tsc1 dramatically drives renal tumor progression.

Figure 2

(A) Kaplan-Meier overall survival analysis for mice of indicated genotypes as a function of weeks after tamoxifen treatment. Cohort size for each mice colony is also indicated. (B) Table showing the incidence of renal adenoma and carcinoma in Tsc1+/− and Tsc1+/− FoxO−/− mice at various stages. ND: not determined.