Table 1.
Plasma and brain 2-AG levels and serum lipid profiles following the 14 d i.p. chronic feeding study. 2-AG levels are presented as mean μg ml−1 and mean ng g−1 ± S.E.M. in plasma and brain respectively. Serum glucose and lipid profiles are expressed as mean mmol/L ± S.E.M.
Vehicle | 2 mg kg−1 | 10 mg kg−1 | Pair-fed | |
---|---|---|---|---|
Plasma 2-AG (μg ml−1) | 18.1 ± 3.5 | 28.4 ± 7.9 | 12.7 ± 1.0 | 22.3 ± 4.6 |
Hypothalamic 2-AG (ng g−1) | 5.1 ± 0.4 | 7.1 ± 0.7 | 6.4 ± 0.4 | 6.0 ± 0.4 |
Glucose (mmol L−1) | 12.0 ± 1.2 | 12.0 ± 0.2 | 13.4 ± 0.8 | 11.5 ± 0.5 |
Triglycerides (mmol L−1) | 1.4 ± 0.4 | 1.2 ± 0.3 | 1.4 ± 0.3 | 1.1 ± 0.3 |
Total Cholesterol (mmol L−1) | 1.7 ± 0.09 | 1.65 ± 0.1 | 1.65 ± 0.15 | 1.75 ± 0.12 |
HDL Cholesterol (mmol L−1) | 1.24 ± 0.07 | 1.19 ± 0.01 | 1.13 ± 0.11 | 1.33 ± 0.13 |